Publications of S. Ravichandran, Ph.D.
Interferon gamma: Ancestors kept their tradition, Ram Savan,
S. Ravichandran, Jack R. Collins, Masahiro Sakai and Howard
A. Young, submitted to Genes and Immunity (2007)
Pharmacophore Modeling of Stereoselective Binding to the
Human Organic Cation Transporter (hOCT1), Ruin Moaddel,
S. Ravichandran, Federica Bighi, Rika Yamaguchi and Irving W. Wainer,
British Journal of Pharmacology, 151(8), 1305-14 2007
Interaction of Noncompetitive Inhibitors with an Immobilized
alpha3beta2 Nicotinic Acetylcholine Receptor Investigated by
Affinity Chromatography and Molecular Docking, Krzysztof Jozwiak,
S. Ravichandran, Jack R. Collins, Ruin Moaddel and Irving W. Wainer,
Journal of Medicinal Chemistry, 50(24), 6279-6283 2007
Computer Simulated Screening of Dentin Bonding Primer Monomers
through Analysis of their Chemical Functions and their
Spatial 3-D Alignment, J. Vaidyanathan, T. K. Vaidyanathan,
and S.Ravichandran, Journal of Biomedical Materials Research
Part B: Applied Biomaterials, 2007 (Accepted).
Computational analysis of adhesion of primer ligands to
dentinal Collagen: Effect of Spacer groups in ligand
and amino acid residue sequence differences in collagen
J. Vaidyanathan, S. Ravichandran and T. K. Vaidyanathan,
Current Drug Discovery Technologies, Volume 4(3), 150-161, 2007.
A Computational and Experimental Analysis of Ligand
Binding to to type 1 collagen,
J. Vaidyanathan, T. K. Vaidyanathan,
N. Ramasubbu and Sarangan Ravichandran,
Current Computer-Aided Drug Design 1(4),397-422, (2005).
Qualitative assessment of IC50 values of inhibitors of the
neuronal nicotinic acetylcholine receptor using a single
chromatographic experiment and multivariate cluster analysis
J. Chromatogr B Analyt Technol Biomed Life Sci. 2005 May
5;819(1):169-74
ATP-Regulated Module (ARM) of the Atrial Natriuretic Factor
Receptor Guanylate Cyclase, Teresa Duda, V. Venkataraman,
S. Ravichandran and R.K. Sharma, Peptides, 26 (6), 969-984 (2005)
Cbl-b interacts with ubiquitinated proteins; differential functions
of the UBA domains of c-Cbl and Cbl-b, Davies GC, Ettenberg SA,
Coats AO, Mussante M, Ravichandran S, Collins J, Nau MM,
Lipkowitz S., Oncogene. Sep 16;23(42):7104-15 (2004)
Interaction of noncompetitive inhibitors with an immobilized
alpha3beta4 nicotinic acetylcholine receptor investigated by
affinity chromatography, quantitative-structure activity
relationship analysis, and molecular docking, Krzystof Jozawiak,
S. Ravichandran, J.R. Collins and I.W. Wainer, Journal of
Medicinal Chemistry, J. Med Chem. Jul 29;47(16):4008-21 (2004)
J. Vaidyanathan, H. Joo, T.K. Vaidyanathan, C. Kasinathan and
S. Ravichandran, Proceedings of the 25th annual Meeting of the
Adhesion Society and the Second World Congress on Adhesion and
Related Phenomena, The Adhesion Society, pp 267-269 (2002)
Jayalakshmi Vaidyanathan, Trithala K. Vaidyanathan, Chinnaswami
Kasinathan, Sarangan Ravichandran, Joshua Simon, “Biomimetic
Recognition and in vitro Immunochemical Confirmation of
Ligand Binding to Collagen”, Society for Biomaterials 28th
Annual Meeting, Tampa, FL, April 24-27 (2002)
S. Ravichandran, J. D. Madura and J. Talbot, “A Brownian dynamics
study of the initial stages of Hen-Egg white Lysozyme adsorption
at a solid interface, The Journal of Physical Chemistry B 105:
3610-3613 (2001)
R. Vasanthi, S. Ravichandran and B. Bagchi, “Anisotropic diffusion
of tagged spheres near the isotropic-nematic transition” ,
J. Chem. Phys. 115: 10022-10028 (2001)
R. Vasanthi, S. Ravichandran and B. Bagchi, Needle-like motion
of prolate ellipsoids in the sea of spheres,
J. Chem. Phys. 114: 7989-7992 (2001)
S. Ravichandran and J. Talbot, Simulating protein adsorption using
detailed molecular models, 219th Annual National Meeting of the
American Chemical Society, San Francisco, CA, Abstracts of
ACS, 219:165-Comp (2000)
S. Ravichandran and J. Talbot, “Mobility of Proteins: A Brownian
Dynamics Study”, Biophysical Journal 78:110-120 (2000)
S. Ravichandran and B. Bagchi, “Anisotropic Diffusion of Non-Spherical
Molecules in Dense Liquids: A Molecular Dynamics Simulation of
Isolated Ellipsoids in the Sea of Spheres”,
J. Chem. Phys. 111:7505-7511 (1999)
S. Ravichandran, A. Perera, M. Moreau and B. Bagchi, “Universality
in the Fast Orientational Relaxation Near Isotropic-Nematic
Transition”, J. Chem. Phys., 109, (1998)
S. Ravichandran, A. Perera, M. Moreau and B. Bagchi, “Translational
and Rotational Motion in Molecular Liquids: A Computer Simulation
Study of Lennard-Jones Ellipsoids”, J. Chem. Phys.,
107, 8469-8475 (1997)
A. Perera, S. Ravichandran, M. Moreau and B. Bagchi, “Single
Particle and Collective Orientational Relaxation in an Anisotropic
Liquid Near the Isotropic-Nematic Transition”, J. Chem. Phys.,
106, 1280-1283 (1997)
S. Ravichandran and B. Bagchi, “Orientational Relaxation in a
Random Dipolar Lattice: Wavenumber and Frequency Dependence”,
Phys. Rev. E., 54, 3693-3706 (1996)
S. Ravichandran and B. Bagchi, “Orientational Dynamics in Random
Dipolar Lattice: Role of Spatial Density Fluctuations in Super-Cooled
Liquids”, Phy. Rev. Lett., 76, (1996)
S. Ravichandran, “Computer Simulation Studies of Orientational
Relaxation in Strongly Correlated Dipolar Systems”, Journal of
Indian Institute of Science (1995)
S. Ravichandran, B. Bagchi, “Orientational Relaxation in Dipolar
Systems: How much Do We Understand the Role of Correlations?”,
International Reviews in Physical Chemistry, 14, 271-314 (1995)
S. Ravichandran, S. Roy and B. Bagchi, “Collective Effects on
Single Particle Orientational Relaxation in Slow Dipolar Liquids”,
J. Phys. Chem., 99, 2489-2501 (1995)
S. Ravichandran and B. Bagchi, “Molecular Dynamics Simulations
of Orientational Relaxation in Dipolar Lattice: Lack of Diffusive
Decay for Second and Higher Rank Correlation Functions”,
J. Phys. Chem., 98, 11242-11245 (1994)
S. Ravichandran and B. Bagchi, “Rank-Dependence of Orientational
Relaxation in Dipolar Systems”,
J. Phys. Chem., 98, 2729-2731 (1994)
S. Ravichandran and B. Bagchi, “Non-exponential Orientational
Relaxation in Dipolar Solids: The Role of Dipolar Interactions
and Dielectric Friction”, J. Molec. Str., 327, 247-254 (1994)
Meetings & Conferences
Validating Modeling and Experimental Methods to Enable
Drug Discovery, April 19-21, NIST, Gaithersburg, MD 2006
Workshop report on validating modeling and experimental methods
to enable drug discovery, Anne M. Chaka et al, 232nd ACS
Meeting, San Francisco, CA, SEP 10-14, 2006
Enantioselectivity of dextromethorphan and
levomethorphan on two subtypes of nicotinic
acetylcholine receptor tested by affinity chromatography,
functional and molecular modeling techniques.
Krzysztof Jozwiak, Irving W. Wainer,
S. Ravichandran, Jack. R. Collins,
16th International Symposium on chirality,
New York, NY, Accepted 07/11 (2004)
A new technology for identification of non-competitive
inhibitors of nicotinic acetylcholine receptor, K. Jozwiak,
I.W. Wainer, S. Ravichandran, and J. Collins, Experimental
biology 2004, Washington DC, 04/17 (2004)
The analysis of interactions of some non-competitive
inhibitors with the nicotinic acetylcholine receptor.
Krzysztof Jozwiak, Sarangan Ravichandran, Irving W. Wainer,
Jack. R. Collins, 48th Annual Meeting of Biophysics Society,
Baltimore 02/14 (2004)
K. Jozwiak, S. Ravichandran, J.R. Collins and I.W. Wainer,
Molecular interactions of ?3?4 nicotinic acetylcholine receptor
(nAChR) with its luminal non-competitive inhibitors: Comparison
of experimental and chromatographic data with in silico docking
studies, American Society for pharmacology and experimental
therapeutics, San Diego, CA. 04/2003 (Presented in the
Translating the Genome: Neurobiology section)
S. Ravichandran, J.D. Madura and J. Talbot, Brownian Dynamics
Simulation of Protein Adsorption: A Detailed Molecular Modeling
Approach, Centre Europeen de Calcul Atomique et Moleculaire
(CECAM) conference on ``Molecular Modeling of Proteins at
Interfaces" held in Lyon, France, 10/1999 (Invited Presentation)
S. Ravichandran, Simulating Protein Adsorption Using Detailed
Molecular Models, NIH project review meeting, Duquesne University,
Pittsburgh, PA, 12/1999
S. Ravichandran and J. Talbot, Brownian Dynamics Simulations
of Adsorbed Lysozyme, American Institute of Chemical Engineers
(AIChE) Annual Meeting, Miami Beach, 11/1998
S. Ravichandran and B. Bagchi, Molecular dynamics study of
orientational relaxation near the isotropic-nematic transition,
Gordon Research Conference on Computational Chemistry,
New Hampshire, 07/1998
S.Ravichandran and B. Bagchi, Molecular Dynamics Simulations of
Orientational Relaxation, Annual Theoretical Chemistry Conference,
Pune, India, 01/1995
S. Ravichandran and B. Bagchi, A Study of the Rank (l) Dependence
of Orientational Relaxation: Comparison Between Theories and
Simulation of a Brownian lattice'', Trombay Symposium on Radiation
and Photochemistry, Reprints Vol 2, 382, Trombay, India (1994)
TALK(s) & POSTERS
Pharmacophore Modeling in Two Different Systems: Understanding
Stereoselective Binding in hOCT1 and Primer Adhesion in Dentinal
Collagen, S. Ravichandran, Accelrys Science Forum, Princeton,
NJ (25 Oct, 2007)
Pharmacophore Modeling of Stereoselective Inhibitor Binding Site
of the hOCT1, Sarangan Ravichandran, R. Moaddel, F. Bighi,
J.R. Collins, R. Yamaguchi, I.W. Wainer, Presented in the 51st
Biophysical Society Annual Meeting, March 3-7, Baltimore 2007
J. Vaidyanathan and T.K. Vaidyanathan, and S. Ravichandran
Understanding Dentinal Adhesion Using Common
Features (HipHop) Hypothesis: An Active A nalog
Approach, BridgeWater, NJ (Sep 25, 2006)
S. Ravichandran, Genetic Algorithm as a Tool for Modeling Biomolecular
Processes, Department of Cell Biology, Stratford, UMDNJ (Jan 31, 2006)
S. Ravichandran, "Linking Animation and Computation in BioMedical
Research", SW Game Technologies, A270Tech Business Networking,
Gaithersburg, MD (Nov 15, 2005)
Wolinella Succinogenes L-Asparaginase: How much do we know?
S. Ravichandran, NCI-Frederick (2002)
S. Ravichandran, Brownian dynamics simulation of protein
adsorption: A detailed molecular modeling approach, National
Institute for Occupational Safety and Health (NIOSH),
Morgantown, WV, 08/2000
S. Ravichandran and J. Talbot Simulating protein adsorption:
A molecular modeling approach, University of Medicine and
Dentistry of New Jersey, Newark, NJ, 08/2000
S. Ravichandran Brownian Dynamics Simulation of Lysozyme
Adsorption, Pittsburgh Supercomputing Center, Pittsburgh,
PA, 02/1999
S. Ravichandran Orientational Relaxation in a Random Dipolar
Lattice: Wave Number and Frequency Dependence, Laboratoire de
Physique Theorique des Liquides Universite Pierre et Marie
Curie, Paris, France, 11/1996
S. Ravichandran Computer simulation studies of orientational
relaxation in strongly correlated dipolar systems, Solid State
& Structural Chemistry Unit, Indian Institute of Science,
Bangalore, India, 06/1995